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產(chǎn)品名稱

SB 207499 - Cilomilast | Ariflo

產(chǎn)品貨號

Axon 1592 CAS [153259-65-5] MF C20H25NO4MW 343.42 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Selective and orally active inhibitor of phosphodiesterase-4 (PDE4); a potential agent for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD); a second generation PDE4 inhibitor, reduces tumor necrosis factor α and interleukin-4 production in vivo References Certificates Categories Extra info TJ Torphy et al. Ariflo (SB 207499), a second generation phosphodiesterase 4 inhibitor for the treatment of asthma and COPD: from concept to clinic. Pulmonary Pharmacol. Ther. 1999, 12(2), 131-135. ? H Ochiai et al. Highly potent PDE4 inhibitors with therapeutic potential. Bioorg. Med. Chem. Lett. 2004, 14(1), 207-210. ? SB Christensen et al. 1,4-Cyclohexanecarboxylates:?Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma.?J. Med. Chem. 1998, 41(6), 821. ? DE Griswold etal. SB 207499 (Ariflo), a Second Generation Phosphodiesterase 4 Inhibitor, Reduces Tumor Necrosis Factor α and Interleukin-4 Production in vivo. J. Pharmacol. Exp. Ther. 1998, 287(2), 705-711. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Pain & Inflammation EC 3.1.4.53 PDE PDE4 inhibitor Chemical name 4-Cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid Parent CAS No. [153259-65-5] Order Size Unit Price Stock 5 mg €90.00 In Stock

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

SB 207499 - Cilomilast | Ariflo

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1592

CAS [153259-65-5]

MF C20H25NO4
MW 343.42

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

SB 207499

Description

Selective and orally active inhibitor of phosphodiesterase-4 (PDE4); a potential agent for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD); a second generation PDE4 inhibitor, reduces tumor necrosis factor α and interleukin-4 production in vivo

TJ Torphy et al. Ariflo (SB 207499), a second generation phosphodiesterase 4 inhibitor for the treatment of asthma and COPD: from concept to clinic. Pulmonary Pharmacol. Ther. 1999, 12(2), 131-135.

H Ochiai et al. Highly potent PDE4 inhibitors with therapeutic potential. Bioorg. Med. Chem. Lett. 2004, 14(1), 207-210.

SB Christensen et al. 1,4-Cyclohexanecarboxylates:?Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma.?J. Med. Chem. 1998, 41(6), 821.

DE Griswold etal. SB 207499 (Ariflo), a Second Generation Phosphodiesterase 4 Inhibitor, Reduces Tumor Necrosis Factor α and Interleukin-4 Production in vivo.
J. Pharmacol. Exp. Ther. 1998, 287(2), 705-711.

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology CNS Pain & Inflammation EC 3.1.4.53 PDE

PDE4 inhibitor

Chemical name

4-Cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid

Parent CAS No.

[153259-65-5]

產(chǎn)品資料

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