PRODUCT NUMBER:

Species Reactivity: Human

Host: Rabbit

Immunogen Source: Human Liver

Form: Ig Fraction (Standard Antisera) obtained by ammonium sulfate precipitation.

Buffer: phosphate buffered saline with 0.05% NaN3 as a preservative

Storage: +2 to 8°C

Protein Concentration: 9.15 mg/mL

Working Dilution: >1:512 by indirect ELISA

Western Blot: at a dilution of 1:8000, the antibody reacts to 0.6 and 1.25 ug purified human liver cathepsin L and does not react with purified cathepsins B, D, or H.

The Cathepsin L immunogen used to prepare this antibody was purified in the Athens Research & Technology laboratory. It is a native protein, whole molecule, isolated from human liver.

PLEASE NOTE: This product is a laboratory reagent and is not to be administered to humans or used for any drug purpose. For research use only.

References:

Chung C, Puthanveetil P, Ory DS, Lieberman AP.
Genetic and pharmacological evidence implicates cathepsins in Niemann-Pick C cerebellar degeneration.
Hum Mol Genet. 2016 Apr 1;25(7):1434-46. doi: 10.1093/hmg/ddw025. Epub 2016 Jan 28.