| 產(chǎn)品名稱 | Protein Phosphatase, Mg2+/Mn2+ Dependent 1F (PPM1F) Antibody | ||||||||||||||||||||||||||||||||
| 產(chǎn)品貨號 | Catalogue No: abx033963 | ||||||||||||||||||||||||||||||||
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 | ||||||||||||||||||||||||||||||||
| 產(chǎn)品規(guī)格 | Available Options * Size: 80 μl 400 μl | ||||||||||||||||||||||||||||||||
| 產(chǎn)品品牌 | abbexa | ||||||||||||||||||||||||||||||||
| 產(chǎn)品概述 | |||||||||||||||||||||||||||||||||
| 產(chǎn)品詳情 |
PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.
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| 產(chǎn)品資料 | 下載鏈接 |
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