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Phospho-Catenin beta (Thr41/S45) Antibody detects endogenous levels of Catenin beta only when phosphorylated at Threonine 41/Sine 45. Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.

Target	Catenin beta (pT41/S45)
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Purification	Purified by affinity chromatography.
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P35222
GeneID	1499
Gene Symbol	CTNNB1
OMIM	116806
HGNC	2514
Ensembl	ENSG00000168036
Buffer	PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.