| 產(chǎn)品名稱 | Fpg, New England Biolabs |
| 產(chǎn)品貨號(hào) | M0240L |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià),電話:010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | vwr |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
Fpg (formamidopyrimidine [fapy]-DNA glycosylase), also known as 8-oxoguanine DNA glycosylase, acts both as an N-glycosylase and an?AP-lyase
The N-glycosylase activity releases damaged purines from double-stranded DNA, generating an apurinic (AP) site. The AP-lyase activity cleaves both 3′ and 5′ to the AP site thereby removing the AP site and leaving a 1-base gap with a 5′ and 3′ phosphate. Some of the damaged bases recognized and removed by Fpg include 7, 8-dihydro-8-oxoguanine (8-oxoguanine), 8-oxoadenine, fapy-guanine, methy-fapy-guanine, fapy-adenine, aflatoxin B1-fapy-guanine, 5-hydroxy-cytosine and 5-hydroxy-uracil.
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