| 產(chǎn)品名稱 | Anti-CD86 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: PO3.1] |
| 產(chǎn)品貨號 | 50-0861-U100 |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | vwr |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
The PO3.1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
The PO3.1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.
Type: Primary
Antigen: CD86 Clonality: Monoclonal Clone: PO3.1 Conjugation: PE (Phycoerythrin) Epitope: Host: Rat Isotype: IgG2b Reactivity: |
| 產(chǎn)品資料 |
