| 產(chǎn)品名稱 | Anti-CD80 Armenian Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: 16-10A1] |
| 產(chǎn)品貨號 | 20-0801-U025 |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | vwr |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
Type: Primary
Antigen: CD80 Clonality: Monoclonal Clone: 16-10A1 Conjugation: APC (Allophycocyanin) Epitope: Host: Armenian Hamster Isotype: IgG Reactivity: |
| 產(chǎn)品資料 |
