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產(chǎn)品名稱(chēng)

PYR41 from CAYMAN CHEMICAL COMPANY

產(chǎn)品貨號(hào)

15226-10

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

10 mg

產(chǎn)品品牌

CAYMAN CHEMICAL COMPANY

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	PYR41
Description	An irreversible inhibitor of ubiquitin-activating enzyme (E1; IC50 = 50 = 6.4 μM); selective for E1 over E2 but does inhibit autoubiquitination of the HECT domain E3 Nedd4 at 50 μM; inhibits proteasome-dependent and -independent ubiquitination and protein degradation at 50 μM; preferentially induces apoptosis of E1A-transformed RPE cells expressing wild-type p53 over non-transformed RPE cells at 1-20 μM; also increases net cellular sumoylation and irreversibly cross-links proteins such as JAK2 and Bcr-Abl
Size	10 mg
Concentration	n/a
Applications	n/a
Other Names	PYR-41 E-1 2 3 auto-ubiquitination NFκB TRAF-6 p-53 JAK-2 Bcrabl Tumor necrosis factor janus kinase 2
Gene, Accession, CAS #	CAS: 418805-02-4
Catalog #	15226-10
Price
Order / More Info	PYR41 from CAYMAN CHEMICAL COMPANY
Product Specific References	n/a
產(chǎn)品資料

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