| 產(chǎn)品詳情 |
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| Antigenic Specificity | MYD88 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b,k |
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| Format | purified |
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| Size | 100ul, 50ul |
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| Concentration | n/a |
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| Applications | ELISA, WB, ICC/IF, Flow cytometry |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Myeloid differentiation primary response gene 88 (MYD88) is adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. |
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| Immunogen | Recombinant human MYD88 (1-309aa) purified from E. coli |
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| Other Names | Myeloid differentiation primary response protein MyD88, MYD88D |
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| Gene, Accession # | NP 002459 |
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| Catalog # | ATGA0247 |
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| Price | |
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| Order / More Info | MYD88 Antibody from ATGen |
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| Product Specific References | n/a |
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