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產(chǎn)品名稱

Recombinant Mouse IL-12 (p70) (carrier-free) from BIOLEGEND

產(chǎn)品貨號(hào)

577008

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Mouse IL-12 (p70) (carrier-free)
Description	IL12 (p70) is a disulfide-linked heterodimer composed of unrelated p40 (glycosylated) and p35 subunits. IL-12 acts as a growth factor for activated human T and NK cells, enhance the lytic activity of human NK cells, and stimulate the production of IFNg, by resting human PBMC. IL-12R is formed by two chains, IL-12Rβ1 and IL-12Rβ2. IL-12Rβ1 is associated with the Janus kinase (Jak) Tyk2 and binds IL-12 p40; IL-12Rβ2 is associated with Jak2 and binds either the heterodimer or the p35 chain. Signaling through the IL-12 receptor complex induces phosphorylation, dimerization, and nuclear translocation of several signal transducer and activator of transcription (STAT) family members (STAT1, 3, 4, 5), but most of the biological responses to IL-12 have been attributed to STAT4.
Size	500 μg
Concentration	n/a
Applications	BA
Other Names	Interleukin-12 p70, p40 and p35 cystine linked subunits, CLMF, NKSF, TcMF, TSF
Gene, Accession, CAS #	Gene ID: 16159, 16160
Catalog #	577008
Price
Order / More Info	Recombinant Mouse IL-12 (p70) (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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