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        產(chǎn)品名稱 RAB32, 1-225aa, Human, His tag, E.coli from ATGen
        產(chǎn)品貨號(hào) ATGP1246
        產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
        產(chǎn)品規(guī)格 0.5mg, 100ug, 20ug
        產(chǎn)品品牌 ATGen
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Product NameRAB32, 1-225aa, Human, His tag, E.coli
        DescriptionPurity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 200mM NaCl, 2mM EDTA. RAB32 belongs to the small GTPase superfamily. RAB32 modulates ER calcium handling and disrupts the specific enrichment of calnexin on the MAM (mitochondria-associated membrane), while not affecting the ER distribution of protein-disulfide isomerase and mitofusin-2. Also, RAB32 determines the targeting of PKA (cAMP-dependent protein kinase) to mitochondrial and ER membranes and through its overexpression or inactivation increases the phosphorylation of Bad and of Drp1. Through a combination of its functions as a PKA-anchoring protein and a regulator of MAM properties, the activity and expression level of RAB32 determine the speed of apoptosis onset. Recombinant human RAB32 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
        Size0.5mg, 100ug, 20ug
        Concentrationn/a
        ApplicationsSDS-PAGE
        Other NamesRas-related protein Rab-32
        Gene, Accession, CAS #NP 006825
        Catalog #ATGP1246
        Price
        Order / More InfoRAB32, 1-225aa, Human, His tag, E.coli from ATGen
        Product Specific Referencesn/a
        產(chǎn)品資料
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