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產(chǎn)品名稱

LINGO, 241-337aa, Human, His tag, E.coli (Denatured) from ATGen

產(chǎn)品貨號

ATGP3011

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

0.5mg, 100ug, 20ug

產(chǎn)品品牌

ATGen

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	LINGO, 241-337aa, Human, His tag, E.coli (Denatured)
Description	Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol. Lingo1 also known as Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein1. LINGO-1 is primarily expressed in neuronal tissue, and most abundantly in cortex. It has been implicated in the inhibition of axon regeneration through a ternary complex formed with NgR1 (ligand-binding subunit) and p75 (signal transducing subunit). The inhibitory action is achieved through RhoA-GTP upregulation in response to the presence of MOG, MAG or Nogo-66 in the central nervous system. LINGO-1 also inhibits oligodendrocyte precursor differentiation and myelination, by a mechanism that also involves activation of RhoA, but which apparently does not require 75 or NgR1.Recombinant human LINGO1 protein, was expressed in E.coli
Size	0.5mg, 100ug, 20ug
Concentration	n/a
Applications	SDS-PAGE
Other Names	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein1, LERN1, LRRN6A, uNQ201
Gene, Accession, CAS #	NP 116197
Catalog #	ATGP3011
Price
Order / More Info	LINGO, 241-337aa, Human, His tag, E.coli (Denatured) from ATGen
Product Specific References	n/a
產(chǎn)品資料

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