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產(chǎn)品名稱(chēng)

uLBP2, 26-216aa, Human, His tag, E.coli (Denatured) from ATGen

產(chǎn)品貨號(hào)

ATGP1592

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

0.5mg, 100ug, 20ug

產(chǎn)品品牌

ATGen

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	uLBP2, 26-216aa, Human, His tag, E.coli (Denatured)
Description	Purity: > 85% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 2M urea, 0.2M NaCl, 2mM DTT. uLBP2, also known as NKG2D ligand 2, belongs to the MHC class I family. This protein is ligand for the NKG2D receptor, together with at least uLBP1 and uLBP3. uLBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of uLBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein uL16. The interaction with uL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. uL16 also causes uLBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. Recombinant human uLBP2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Size	0.5mg, 100ug, 20ug
Concentration	n/a
Applications	SDS-PAGE
Other Names	NKG2D ligand 2, N2DL2, RAET1H
Gene, Accession, CAS #	NP 079493
Catalog #	ATGP1592
Price
Order / More Info	uLBP2, 26-216aa, Human, His tag, E.coli (Denatured) from ATGen
Product Specific References	n/a
產(chǎn)品資料

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