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產(chǎn)品名稱

Recombinant Human NEGR-1 (carrier-free) from BIOLEGEND

產(chǎn)品貨號(hào)

718802

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

10 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Human NEGR-1 (carrier-free)
Description	Neuronal growth regulator-1 (NEGR-1) is a 46 kDa member of immunoglobulin superfamily of cell adhesion molecules (IgLONs). IgLONs are the most abundant glycoylphosphatidylinositol-anchored proteins expressed in neurons and they include limbic system-associated membrane molecule (LSAMP), neurotrimin (NTM), opioid-binding cell adhesion molecule (OBCAM), and NEGR-1. IgLON proteins contain three immunoglobulin domains, GPI anchor, and 6-7 potential glycosylation sites. IgLONs form hemophilic and heterophilic complexes to modulate cell adhesion and neurite outgrowth. IgLONs play a role in the formation and maintenance of excitatory synapses. NEGR-1 is expressed in the brain, specifically in the cerebrum, brain stem, hippocampus, and cerebellum. It may also function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain. Genome-wide analysis revealed that NEGR1 is associated with human body weight regulation. NEGR1 is also frequently downregulated in various human cancers and is a substrate for metalloproteinase-dependent shedding.? ??
Size	10 μg
Concentration	n/a
Applications	BA
Other Names	Neuronal growth regulator-1, NEGR1, Kilon, IGLON4, neurotractin, Ntra
Gene, Accession, CAS #	Gene ID: 257194
Catalog #	718802
Price
Order / More Info	Recombinant Human NEGR-1 (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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