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產(chǎn)品名稱

LL-37, Human, ELISA kit from HYCULT BIOTECH

產(chǎn)品貨號(hào)

HK321-01

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

1 x 96 det.

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	LL-37, Human, ELISA kit
Description	Cathelicidins are a family of antimicrobial proteins predominantly found in the peroxidase-negative granules of neutrophils. The cathelicidins are synthesized as preproproteins. Within the neutrophils, they are stored in granules as inactive proforms after removal of the signal peptide. The active biologic domains of the cathelicidins generally reside in the C-terminus. The C-terminal antimicrobial peptides are activated when cleaved from the proforms of the cathelicidins by serine proteases from azurophil granules. Human cationic antimicrobial protein (hCAP)18 is the only human cathelicidin identified to date. The antibacterial C-terminus of hCAP-18, LL37 (37 amino acids), has been shown to exert broad antimicrobial activity towards gram-negative as well as gram-positive bacteria and to have synergistic antibacterial effects with the defensins. For instance, deficiency in saliva LL37 accords with occurrence of periodontal disease in patients with morbus Kostmann. Moreover, it functions as a chemotactic agent for neutrophils, monocytes and T cells. LL-37 is markedly resistant to proteolytic degradation and to a limited extent also cytotoxic towards mammalian cells. LL-37 was demonstrated to be present in plasma in levels from 25 - 250 ng/ml and to be enhanced in infectious diseases.
Size	1 x 96 det.
Concentration	n/a
Applications	Immunoassay
Other Names	Sandwich ELISA kit, EIA, enzyme immunoassay, assay
Gene, Accession, CAS #	n/a
Catalog #	HK321-01
Price
Order / More Info	LL-37, Human, ELISA kit from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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