| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | Smad4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 30 μg |
| Concentration | 0.5 mg/ml |
| Applications | Western blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Smad4 Antibody. Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities throμgh interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members. |
| Immunogen | Synthetic peptide corresponding to amino acids residues around 281 of human Smad4 |
| Other Names | DPC4, JIP, MADH4 |
| Gene, Accession # | Gene ID: 4089, Accession: BAB40977 |
| Catalog # | 3464-30T |
| Price | |
| Order / More Info | Smad4 Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
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