| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | mTOR |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 μl |
| Concentration | n/a |
| Applications | Western blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | mTOR Antibody. The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. When sufficient nutrients are available, mTOR responds to a phosphatidic acid-mediated signal to transmit a positive signal to p70 S6 kinase and participate in the inactivation of the eIF4E inhibitor, 4E-BP1. These events result in the translation of specific mRNA subpopulations. mTOR is phosphorylated at Ser2448 via the PI3 kinase/Akt signaling pathway and autophosphorylated at Ser2481. mTOR plays a key role in cell growth and homeostasis and may be abnormally regulated in tumors. For these reasons, mTOR is currently under investigation as a potentia |
| Immunogen | Synthetic peptide of human mTOR |
| Other Names | FRAP1, FK506 binding protein 12-rapamycin associated protein 1; FRAP2, FK506 binding protein 12-rapamycin associated protein 2; RAFT1, RAPT1 |
| Gene, Accession # | Gene ID: 2475, Accession: NP_004949.1 |
| Catalog # | 3786-100 |
| Price | |
| Order / More Info | mTOR Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
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