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產(chǎn)品名稱

PF-06463922 from BIOVISION, INC.

產(chǎn)品貨號

B1169-50

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

50 mg

產(chǎn)品品牌

BIOVISION, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	PF-06463922
Description	PF-06463922 is a potent, selective, brain-penetrant, and high affinity ALK (Anaplastic lymphoma kinase) and ROS1 (c-Ros oncogene 1) inhibitor displaying >100-fold selectivity for ROS1 over panel of 204 other kinases. It has strong activity against all known ALK and ROS1 mutants identified in patients, including the EML4-L1196M mutant of ALK (Ki = < 0.02 nM). It inhibits proliferation of BaF3 cells containing Crizotinib resistant ROS1 mutation in vitro. MW: 406.41. Purity ≥98% by HPLC
Size	50 mg
Concentration	n/a
Applications	n/a
Other Names	(10R)-7-Amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile
Gene, Accession, CAS #	CAS: 1454846-35-5
Catalog #	B1169-50
Price
Order / More Info	PF-06463922 from BIOVISION, INC.
Product Specific References	n/a
產(chǎn)品資料

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