| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | Caspase 3 |
| Clone | RM250 |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | Protein A purified |
| Size | 50 μl |
| Concentration | n/a |
| Applications | IHC, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit monoclonal antibody to detect Caspase-3 in human samples. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-3 is synthesized as an inactive pro-enzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP and DFF). |
| Immunogen | Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-3 is synthesized as an inactive pro-enzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP and DFF). |
| Other Names | CPP32, CASP3, apopain, procaspase3, CPP32B, SCA-1, CPP-32, Apopain, Yama |
| Gene, Accession # | Gene ID: 836, Accession: P42574 |
| Catalog # | A1120-50 |
| Price | |
| Order / More Info | Caspase 3 Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
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