| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | Caspase-9 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 30 μg |
| Concentration | 0.2 mg/ml |
| Applications | Western blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Caspase-9 Antibody. Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase-9/Apaf-1. The complex processes procaspase-9 into a large subunit (35 kDa or 17 kDa) and small (10 kDa) by self-cleavage at D315. Activated caspase-9 further cleaves other caspase members including caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. In addition to self-cleavage, procaspase-9 can also be cleaved in vivo by caspase-3 at D330. The process served as a positive feedback to amplify the apoptotic signal in caspase activation pathway. |
| Immunogen | Synthetic peptide surrounding amino acid 345 of mouse caspase-9 |
| Other Names | CASP-9 , EC 3.4.22.62 , ICE-like apoptotic protease 6 ,ICE-LAP6 ,Apoptotic protease Mch-6 ,Apoptotic protease-activating factor 3 , Apaf-3 |
| Gene, Accession # | Gene ID: 12371, Accession: CAM23133 |
| Catalog # | 3409-30T |
| Price | |
| Order / More Info | Caspase-9 Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
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