| Description | Purity > 90% as determined by SDS-PAGE. MW: 54kDa. Full Length: 1-294aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Arabidopsis thaliana (Mouse-ear cress). Phosphorylates specifically 'Ser-10' of histone H3 in vitro and colocalizes with phosphorylated histone H3 during mitosis. Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle. Colocalizes also with gamma-tubulin and function in microtubule organizing centers (MTOCs). In contrast with the mammalian B-type Aurora, AUR1 has no kinase activity toward 'Ser-28' of histone H3 |
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