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| Antigenic Specificity | CANX |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other |
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| Isotype | n/a |
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| Format | immunoaffinity purified |
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| Size | 400 μg |
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| Concentration | 2 mg/ml |
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| Applications | WB, IF, IHC-P, IHC-F |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Goat polyclonal to CANX (Calnexin) - endoplasmic reticulum (ER) membrane marker. CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Detects a band of 90 kDa by Western blot in the following human (293A, primary fibroblasts, HaCat, HeLa, HMEC-1, Jurkat, MNT1, U-118, rat (TR-iBRB), mouse (3T3, AtT-20, Hepa, Raw264.7), monkey (COS-7) and canine (D17) whole cell lysates. |
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| Immunogen | Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli. |
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| Other Names | calnexin, CALX, CNX, FLJ26570, histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 |
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| Gene, Accession # | CANX, Gene ID: 821 |
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| Catalog # | AB0041-200 |
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| Price | |
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| Order / More Info | CANX Antibody from SICGEN ANTIBODIES |
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| Product Specific References | 1. Pelkonen L, Sato K, Reinisalo M, et al. Mol Pharm. 2017 Mar 6. PMID:28112518, 2. Martins-Marques T, Pinho MJ, Zuzarte M. et al. J Extracell Vesicles. 2016 Sep 29;5:32538. PMID:27702427, 3. Ferreira RRS, MSc Thesis, Coimbra University 2015, 4. Paiva RA, MSc Thesis, Coimbra University 2015, 5. Samtleben S, PhD Thesis, Universitat Wurzburg 2014, 6. Ribot JC, Ribeiro ST, Correia DV, Sousa AE, Silva-Santos B. J Immunol. 2014 Mar, PMID: 24489097, 7. Marques, CIR, MSc Thesis, Coimbra University 2013 |
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