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| Antigenic Specificity | Solute carrier family 22 member 5/SLC22A5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for Solute carrier family 22 member 5(SLC22A5) detection. Tested with WB in Mouse;Rat. No cross reactivity with other proteins. Solute carrier family 22(organic cation/carnitine transporter), member 5, also called SLC22A5 or OCTN2 is a membrane transport protein associated with primary carnitine deficiency. This gene is mapped to 5q31.1. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency(CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of mouse Solute carrier family 22 member 5(531-547aa KQWQIQSQTRMQKDGEE), different from the related rat sequence by two amino acids. |
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| Other Names | Solute carrier family 22 member 5;High-affinity sodium-dependent carnitine cotransporter;Organic cation/carnitine transporter 2;Slc22a5;Octn2; |
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| Gene, Accession # | SLC22A5, UniProt: Q9Z0E8 |
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| Catalog # | PA2174 |
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| Price | |
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| Order / More Info | Solute carrier family 22 member 5/SLC22A5 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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