| Description | Purity >95% by SDS-PAGE, MW: 8 kDa. Stromal cell-derived factor-1 alpha (SDF-1a), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as tumor necrosis factors (TNF), interleukin 1 (IL-1), and lipopolysaccharide (LPS). SDF-1a signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1a share 99% sequence identity. |
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| Other Names | CXCL12, C-X-C motif chemokine 12, HIRH, IRH, SDF-1, SDF-1b, SDF1A, SDF1B, TPAR1, TLSF-a, TLSF-b, SDF-1a, SDF1, Sdf1alpha, Stromal cell-derived factor 1, TLSF, HSDF-1, PBSF, SCYB12 |
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