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| Antigenic Specificity | Antithrombin III/SERPINC1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat (predicted: hamster) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for Antithrombin-III(SERPINC1) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. Serpin peptidase inhibitor, clade C(antithrombin), member 1, also known as Antithrombin III(AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III(93-107aa TFYQHLADSKNDNDN), different from the related mouse and rat sequences by one amino acid. |
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| Other Names | Antithrombin-III;ATIII;Serpin C1;SERPINC1;AT3;PRO0309; |
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| Gene, Accession # | SERPINC1, UniProt: P01008 |
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| Catalog # | PA2218 |
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| Price | |
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| Order / More Info | Antithrombin III/SERPINC1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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