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產(chǎn)品名稱

GN25 from BIOVISION, INC.

產(chǎn)品貨號(hào)

9430-5

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

5 mg

產(chǎn)品品牌

BIOVISION, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	GN25
Description	GN25 blocks Snail binding to p53 and induces p53 expression in cancer cells in a KRas dependent manner. Oncogenic KRas has been shown to inhibit p53 function by inducing Snail to bind and eliminate p53 through exocytosis. At 10 μM, GN25 significantly reduces cell proliferation in KRas mutated A549 and HCT116 cell lines but not in wild type MKN-45 cells. In a xenograft mouse model, 10 mg/kg GN25 yields antitumoral effects by notably reducing tumor size and progression. MW: 322.3. Purity ≥98%
Size	5 mg
Concentration	n/a
Applications	n/a
Other Names	3-?[(1,?4-?dihydro-?5,?8-?dimethoxy-?1,?4-?dioxo-?2-?naphthalenyl)thio]-?propanoic acid
Gene, Accession, CAS #	CAS: 1227401-27-5
Catalog #	9430-5
Price
Order / More Info	GN25 from BIOVISION, INC.
Product Specific References	n/a
產(chǎn)品資料

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