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產(chǎn)品名稱

IBMX from ARBOR ASSAYS, INC.

產(chǎn)品貨號

P019-1GM

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

1 gm

產(chǎn)品品牌

ARBOR ASSAYS, INC.

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	IBMX
Description	IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) with IC50s from 7 to 50 μM for PDE1-5, PDE7, and PDE11. PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP levels, activating cyclic-nucleotide-regulated protein kinases. Methylxanthines, including IBMX, caffeine, and theophylline, bind adenosine receptors, typically antagonizing the suppressive effects of natural agonists. Suppresses alpha-adrenoceptor-mediated 5-HT release from neuroendocrine epithelial cells (IC50 = 1.3 μM).
Size	1 gm
Concentration	n/a
Applications	Activator or Inhibitor
Other Names	PDE inhibitor
Gene, Accession, CAS #	n/a
Catalog #	P019-1GM
Price
Order / More Info	IBMX from ARBOR ASSAYS, INC.
Product Specific References	n/a
產(chǎn)品資料

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