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產(chǎn)品名稱

Recombinant Mouse IL-17A (carrier-free) from BIOLEGEND

產(chǎn)品貨號

576004

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

25 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Mouse IL-17A (carrier-free)
Description	IL-17A was initially identified from a subtracted cDNA library between closely related murine lymphoid cells and called CTLA-8. IL-17A shares 58% homology with an open reading frame of the T-lymphotropic Herpes virus Samirii virus (viral IL-17). IL-17A belongs to a family of cytokines, which has five members; designated IL-17A-F. IL-17 is expressed by a unique lineage of CD4 T cells, Th17 cells. This lineage selectively produces proinflammatory cytokines including IL-17, IL-17F, IL-21, and IL-22. In the mouse, the differentiation of this new lineage is initiated by TGFbeta-1 and IL-6 or IL-21, which activates Stat3 and induces the expression of the transcription factor retinoic acid-related orphan receptors (RORγt and RORα). IL-23, which also activates Stat3, serves to maintain Th17 cells lineage.
Size	25 μg
Concentration	n/a
Applications	BA
Other Names	Interleukin-17A, CTLA-8
Gene, Accession, CAS #	Gene ID: 16171
Catalog #	576004
Price
Order / More Info	Recombinant Mouse IL-17A (carrier-free) from BIOLEGEND
Product Specific References	PubMed: 22156344,22207130,22331300,24412909
產(chǎn)品資料

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