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        產(chǎn)品名稱 Recombinant Mouse IL-17A (carrier-free) from BIOLEGEND
        產(chǎn)品貨號 576006
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 100 μg
        產(chǎn)品品牌 BIOLEGEND
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Product NameRecombinant Mouse IL-17A (carrier-free)
        DescriptionIL-17A was initially identified from a subtracted cDNA library between closely related murine lymphoid cells and called CTLA-8. IL-17A shares 58% homology with an open reading frame of the T-lymphotropic Herpes virus Samirii virus (viral IL-17). IL-17A belongs to a family of cytokines, which has five members; designated IL-17A-F. IL-17 is expressed by a unique lineage of CD4 T cells, Th17 cells. This lineage selectively produces proinflammatory cytokines including IL-17, IL-17F, IL-21, and IL-22. In the mouse, the differentiation of this new lineage is initiated by TGFbeta-1 and IL-6 or IL-21, which activates Stat3 and induces the expression of the transcription factor retinoic acid-related orphan receptors (RORγt and RORα). IL-23, which also activates Stat3, serves to maintain Th17 cells lineage.
        Size100 μg
        Concentrationn/a
        ApplicationsBA
        Other NamesInterleukin-17A, CTLA-8
        Gene, Accession, CAS #Gene ID: 16171
        Catalog #576006
        Price
        Order / More InfoRecombinant Mouse IL-17A (carrier-free) from BIOLEGEND
        Product Specific ReferencesPubMed: 22156344,22207130,22331300,24412909
        產(chǎn)品資料
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