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產(chǎn)品名稱

Recombinant Mouse IL-17A/F Heterodimer (carrier-free) from BIOLEGEND

產(chǎn)品貨號

580808

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Mouse IL-17A/F Heterodimer (carrier-free)
Description	IL-17A/F is part of the IL-17 cytokine family which consists of six structurally related proteins (IL-17A, B, C, D, E, and F). IL-17A is expressed primarily by Th17 cells, a subset of CD4 T cells. IL-17F is most closely related to IL-17A. The two molecules share 50% amino acid sequence homology. Like IL-17A, IL-17F mRNA and protein have been detected in Th17 cells. L-17F and IL-17A exist as a homodimers, adopting a cysteine knot motif formed through the interactions of four cysteines, one of which is responsible for the interchain bonding. IL-17F and IL-17A can form both homodimeric and heterodimeric proteins when expressed in a recombinant system and all forms of the recombinant proteins have in vitro functional activity. Mouse Th17 cells secret IL-17A/F as well as the homodimers IL-17A and IL-17F. IL-17A/F induces IL-6 and KC (CXCL1) production in mouse fibroblast and macrophages.IL-17A/F signals through IL-17A and TRAF6.
Size	500 μg
Concentration	n/a
Applications	BA
Other Names	IL-17A/IL-17F
Gene, Accession, CAS #	Gene ID: 16171, 257630
Catalog #	580808
Price
Order / More Info	Recombinant Mouse IL-17A/F Heterodimer (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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