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| Product Name | M62812 |
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| Description | TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic shock model. Purity 98%. MW (observed): 330.23 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-(2-Aminophenoxy)-1,2-benzisothiazol-3-amine dihydrochloride |
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| Gene, Accession, CAS # | CAS: 613263-00-6 |
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| Catalog # | 5705/10 |
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| Price | |
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| Order / More Info | M62812 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 17588563 |
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