| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | AKT1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human. predicted cross reactivity with mouse, rat, bovine and Xenopus |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 100 μl |
| Concentration | n/a |
| Applications | Western blot, IHC, FACS. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polyclonal Antibody to detect AKT1 in human, mouse, rat, bovine and xenopus samples. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 and Akt 3, which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. They have a pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-? tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Phosphorylation of both residues is important to generat |
| Immunogen | This AKT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-309 amino acids from human AKT1. |
| Other Names | PKB, RAC, Protein kinase B, Protein kinase B alpha, Short PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha |
| Gene, Accession # | Gene ID: 207, Accession: P31749 |
| Catalog # | 6742-100 |
| Price | |
| Order / More Info | AKT1 Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
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