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產(chǎn)品名稱

WM902B Purified Genomic DNA from ROCKLAND IMMUNOCHEMICALS INC.

產(chǎn)品貨號

WM902B-02-5000

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

25 μg

產(chǎn)品品牌

ROCKLAND IMMUNOCHEMICALS INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	WM902B Purified Genomic DNA
Description	DNA was prepared from cell line WM902B. WM902B is a tumorigenic (VGP) primary melanoma cell line with competence for metastasis. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line also expresses PTEN loss of function including hemizygous deletion and R24L mutation at position 24 in the CDK4 gene. The R24L mutation results in an amino acid substitution at codon 24 in CDK4, from an arginine (R) to Leucine (L). This mutation renders the protein resistant to the inhibitory effects of INK4A function. WM902B cells produce xenograft tumors when injected into immunocompromised mice.
Size	25 μg
Concentration	200 ng / μl
Applications	Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis.
Other Names	Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft
Gene, Accession, CAS #	n/a
Catalog #	WM902B-02-5000
Price
Order / More Info	WM902B Purified Genomic DNA from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific References	n/a
產(chǎn)品資料

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