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產(chǎn)品名稱

Recombinant Human CX3CL1 (Fractalkine) (carrier-free) from BIOLEGEND

產(chǎn)品貨號

583406

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Human CX3CL1 (Fractalkine) (carrier-free)
Description	CX3CL1 is a unique chemokine subclass, synthesized as a transmembrane molecule. It consists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane α helix, and a short cytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Soluble CX3CL1 is generated by limited proteolysis on the cell surface, and a disintegrin and metallopeptidase 10 (ADAM10) and ADAM17/tumor necrosis factor-α-converting enzyme (ADAM17/TACE) participate in this shedding. It has been suggested that ADAM10 acts in the constitutive shedding, and ADAM17 acts in response to cell activation. CX3CL1 is associated with the development of different diseases such as rheumatoid arthritis (RA), rheumatoid vasculitis (RV), Sj?gren’s syndrome (SS), systemic lupus erythematosus (SLE), scleroderma, multiple sclerosis, and atherosclerosis. Soluble fractalkine has been detected in the cerebrospinal fluid of patients with neuropsychiatric lupus, and is present at higher levels in the serum of patients with SS, RA, and type 2 diabetes than in control subjects.
Size	100 μg
Concentration	n/a
Applications	BA
Other Names	Small inducible cytokine subfamily D, member 1 (SCYD1), Neurotactin (NTT, NTN)
Gene, Accession, CAS #	Gene ID: 6376
Catalog #	583406
Price
Order / More Info	Recombinant Human CX3CL1 (Fractalkine) (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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