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產(chǎn)品名稱

Recombinant Human Septin-2 (SEPT2) from BIOMATIK

產(chǎn)品貨號(hào)

RPC22995

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100ug

產(chǎn)品品牌

BIOMATIK

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Human Septin-2 (SEPT2)
Description	Purity > 90% as determined by SDS-PAGE. MW: 57.5kDa. Full Length: 1-361aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Size	100ug
Concentration	n/a
Applications	RUO
Other Names	Neural precursor cell expressed developmentally down-regulated protein 5; NEDD-5
Gene, Accession, CAS #	43710, UniProt: Q15019
Catalog #	RPC22995
Price
Order / More Info	Recombinant Human Septin-2 (SEPT2) from BIOMATIK
Product Specific References	n/a
產(chǎn)品資料

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