| 產(chǎn)品詳情 |
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| Antigenic Specificity | Claudin 5/CLDN5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for Claudin-5(CLDN5) detection. Tested with WB in Human;Rat. No cross reactivity with other proteins. Claudin-5(CLDN5) also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80% of VCFS patients. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. What's more, it plays a major role in tight junction-specific obliteration of the intercellular space. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5(191-218aa RPDLSFPVKYSAPRRPTATGDYDKKNYV), different from the related mouse sequence by three amino acids and from the related rat sequence by four amino acids. |
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| Other Names | Claudin-5;Transmembrane protein deleted in VCFS;TMDVCF;CLDN5;AWAL, TMVCF; |
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| Gene, Accession # | CLDN5, UniProt: O00501 |
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| Catalog # | RP1043 |
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| Price | |
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| Order / More Info | Claudin 5/CLDN5 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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