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        產(chǎn)品名稱 WM852 Purified RNA from ROCKLAND IMMUNOCHEMICALS INC.
        產(chǎn)品貨號 WM852-04-0500
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 10 μg
        產(chǎn)品品牌 ROCKLAND IMMUNOCHEMICALS INC.
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Product NameWM852 Purified RNA
        DescriptionTotal RNA was prepared from cell line WM852. WM852 is a metastaic melanoma cell line with epithelial morphology. This cell line was established from the metastatic site (abdomen) in a 63-year -old male. This cell line contains a Q61R mutation at position 61 in the N-RAS gene. The Q61R is the most common NRAS mutation found in melanoma that is thought to occur due to UV and radiation exposure. This mutation leads to production of a constitutively active N-RAS protein that directs cells to grow and divide constantly. This cell line also expresses PTEN loss of function including hemizygous deletion and is wild type for BRAF, c-KIT and CDK4. WM852 cells produce xenograft tumors when injected into immunocompromised mice.
        Size10 μg
        Concentration200 ng / μl
        ApplicationsPurified RNA is suitable for a number of molecular biology applications including but not limited to next generation sequencing and expression library construction, PCR, real-time PCR, microarray analysis, and transfection experiements.
        Other NamesHuman Melanoma, patient derived tumor, tumor models, skin cancer, xenograft
        Gene, Accession, CAS #n/a
        Catalog #WM852-04-0500
        Price
        Order / More InfoWM852 Purified RNA from ROCKLAND IMMUNOCHEMICALS INC.
        Product Specific ReferencesFriedegund Meier et al. Human Melanoma Progression in Skin Reconstructs: Biological Significance of bFGF. Am J Pathol. (2000); 156(1): 193-200. doi: 10.1016/S0002-9440(10)64719-12
        產(chǎn)品資料
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