| 產(chǎn)品詳情 |
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| Product Name | Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 (Cd163), partial |
| Description | Purity > 90% as determined by SDS-PAGE. MW: 34.2kDa. Partial: 86-365aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). Involved in clearance and endocytosis of hoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hoglobin/haptoglobin and subsequent breakdown of he. Binds hoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.After shedding, the soluble form (sCD163) may play an anti-inflammatory role. |
| Size | 100ug |
| Concentration | n/a |
| Applications | RUO |
| Other Names | CD163 |
| Gene, Accession, CAS # | Cd163, UniProt: Q2VLH6 |
| Catalog # | RPC23083 |
| Price | |
| Order / More Info | Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 (Cd163), partial from BIOMATIK |
| Product Specific References | n/a |
| 產(chǎn)品資料 |
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