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| Product Name | L-655,708 |
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| Description | Potent, selective inverse agonist for the benzodiazepine site of GABAA receptors containing the α5 subunit (Ki = 0.45 nM). Displays 50-100-fold selectivity over GABAA receptors containing α1, α2, α3 or α6 subunits in combination with β3 and γ2. Enhances LTP in a mouse hippocampal slice model and increases spatial learning, without displaying proconvulsant activity. Purity 98%. MW (observed): 341.37 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 11,12,13,13a-Tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, ethyl ester |
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| Gene, Accession, CAS # | CAS: 130477-52-0 |
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| Catalog # | 1327/50 |
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| Price | |
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| Order / More Info | L-655,708 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19812324, 23126673, 23380687, 25080596, 25914623, 27500406 |
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