| 產(chǎn)品詳情 |
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| Antigenic Specificity | BoNT B |
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| Clone | GR3G7 |
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| Host Species | Mouse |
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| Reactive Species | Clostridium botulinum |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | flow cytometry, CELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Botulinum neurotoxin type B (BoNT/B) is produced by Clostridium botulinum, a genetically diverse class of anaerobic, spore-forming, gram-positive bacilli. Seven different botulinum toxin groups have been identified serologically and are called botulinum toxin type A,B,C,D,E,F, and G. BoNT/B is a two-chain polypeptide with a 100-kDa heavy chain, which is responsible for neurospecific binding joined by a disulphide bond to a 50-kDa light chain, a zinc-endopeptidase which blocks neurotransmitter release. BoNT/B is one of the most poisonous naturally occurring substances. It inhibits acetylcholine release from neuromuscular junctions while it is used as an important therapeutic mainstay in the treatment of spasticity disorders and as a cosmetic treatment. |
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| Immunogen | cDNA |
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| Other Names | C. botulinum neurotoxin type B |
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| Gene, Accession # | n/a |
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| Catalog # | GM-0701 |
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| Price | |
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| Order / More Info | BoNT B Antibody from ALDEVRON FREIBURG GmbH |
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| Product Specific References | n/a |
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