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產(chǎn)品名稱

LY364947 from BIOVISION, INC.

產(chǎn)品貨號

2646-5

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

5 mg

產(chǎn)品品牌

BIOVISION, INC.

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	LY364947
Description	LY364947 is a selective inhibitor of TGF-β RI (TGFR-I, TβR-I, ALK-5), with an IC50 value of 59 nM. LY364947 only weakly inhibits TGF-β RII (IC50 = 400 nM), p38 MAPK (IC50 = 740 nM), and mixed lineage kinase-7 (MLK-7; IC50 = 1,400 nM).It inhibits TGF-β-induced cell growth (IC50 = 89 nM) in NIH 3T3 mouse fibroblasts and TGF-β-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells. MW: 272.31. Purity ≥98% by HPLC
Size	5 mg
Concentration	n/a
Applications	n/a
Other Names	4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-quinoline; HTS 466284
Gene, Accession, CAS #	CAS: 396129-53-6
Catalog #	2646-5
Price
Order / More Info	LY364947 from BIOVISION, INC.
Product Specific References	n/a
產(chǎn)品資料

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