| 產(chǎn)品詳情 |
| Edit |   |
| Product Name | LY255283 |
| Description | Purity >98%. Antagonists of the chemotactic and inflammatory lipoxygenase product leukotriene B4 (LTB4 ) have been potential drug development targets for several years. The tetrazole LY255283 is a competitive antagonist of the BLT2 receptor. It displaces radiolabeled LTB4 from guinea pig lung membrane, with an IC50 of about 100 nM. LY255283 exhibits IC50 values of ~950 nM and >10 μM at human recombinant BLT2 and BLT1 receptors, respectively. LY255283 inhibits eosinophil chemotaxis by 80% at a concentration of 10 μM, and inhibits the binding of radiolabeled LTB4 to eosinophil membranes with an IC50 of 260 nM. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1-[5-ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]-ethanone |
| Gene, Accession, CAS # | CAS: 117690-79-6 |
| Catalog # | LS-H8554 |
| Price | |
| Order / More Info | LY255283 from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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