| Description | A hydrophobic derivative of the class I and class II HDAC inhibitor SAHA that demonstrates >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay; inhibits proliferation of SK-BR-3 breast-derived, HT29 colon-derived, and U937 leukemia cell lines with EC50 values of 1.1, 0.95, and 0.12 μM, respectively |
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