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產(chǎn)品名稱

Oleoyl 3-carbacyclic Phosphatidic Acid from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號

LS-H9162

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Oleoyl 3-carbacyclic Phosphatidic Acid
Description	Purity >95%. Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn -2 hydroxy group forms a 5-membered ring with the sn -3 phosphate. Carba-derivatives of cPA (ccPA) are modified at the sn -2 (2-ccPA) or sn -3 (3-ccPA) linkage, preventing the opening of cPA to produce lysophosphatidic acid (LPA). Oleoyl 3-Carbacyclic Phosphatidic Acid (3-ccPA 18:1) is a cyclic LPA analog that contains the 18:1 fatty acid, oleate, at the sn -1 position of the glycerol backbone. At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (90.1%) or LPA (99.9%) without affecting proliferation. 3-ccPA 18:1, at 0.1-1.0 μM, significantly inhibits autotaxin, an enzyme that is important in cancer cell survival, growth, migration, invasion, and metastasis.
Size	n/a
Concentration	n/a
Applications	n/a
Other Names	(9Z)-9-octadecenoic acid, (2-hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methyl ester, 3-ccPA 18:1
Gene, Accession, CAS #	CAS: 779333-58-3
Catalog #	LS-H9162
Price
Order / More Info	Oleoyl 3-carbacyclic Phosphatidic Acid from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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