| Edit |   |
|---|
| Product Name | Cxcl12, 22-89aa, Mouse, His tag, E.coli |
|---|
| Description | Purity: > 95% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH7.4) containing 10% glycerol. Cxcl12 also known as stromal cell-derived factor 1 isoform alpha. This protein acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. It stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. This protein inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Cxcl12 protein plays a protective role after myocardial infarction. It induces down-regulation and internalization of ACKR3 expressed in various cells. Recombinant mouse Cxcl12, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques |
|---|
| Size | 100ug, 20ug, 4ug |
|---|
| Concentration | n/a |
|---|
| Applications | SDS-PAGE |
|---|
| Other Names | Stromal cell-derived factor 1 isoform alpha, Pbsf, Scyb12, Sdf1, Tlsf, Tpar1 |
|---|
| Gene, Accession, CAS # | NP 068350 |
|---|
| Catalog # | ATGP3159 |
|---|
| Price | |
|---|
| Order / More Info | Cxcl12, 22-89aa, Mouse, His tag, E.coli from ATGen |
|---|
| Product Specific References | n/a |
|---|