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產(chǎn)品名稱

Palmitoyl 3-carbacyclic Phosphatidic Acid from LIFESPAN BIOSCIENCES INC.

產(chǎn)品貨號

LS-H9261

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

n/a

產(chǎn)品品牌

LIFESPAN BIOSCIENCES INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Palmitoyl 3-carbacyclic Phosphatidic Acid
Description	Purity >95%. Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn -2 hydroxy group forms a 5-membered ring with the sn -3 phosphate. Carba-derivatives of cPA (ccPA) are modified at the sn -2 (2-ccPA) or sn -3 (3-ccPA) linkage, preventing the opening of cPA to produce LPA. Palmitoyl 3-ccPA is a cyclic LPA analog that contains the 16:0 fatty acid, palmitate, at the sn -1 position of the glycerol backbone. At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (81.9%) or LPA (98.9%) without affecting proliferation. 3-ccPA 16:0, at 0.1-25 μM, significantly inhibits autotaxin, an enzyme that is important in cancer cell survival, growth, migration, invasion and metastasis.
Size	n/a
Concentration	n/a
Applications	n/a
Other Names	(2-hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methyl ester-hexadecanoic acid, 3-ccPA 16:0
Gene, Accession, CAS #	CAS: 476310-22-2
Catalog #	LS-H9261
Price
Order / More Info	Palmitoyl 3-carbacyclic Phosphatidic Acid from LIFESPAN BIOSCIENCES INC.
Product Specific References	n/a
產(chǎn)品資料

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