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產品名稱

ICAM-1, Human Antibody from HYCULT BIOTECH

產品貨號

HM2104BT

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

50 μg

產品品牌

HYCULT BIOTECH

產品概述

產品詳情

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Antigenic Specificity	ICAM-1, Human
Clone	HM.2
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	biotin conjugate
Size	50 μg
Concentration	100 μg/ml
Applications	frozen sections, FC, immunoassay, IF, IP, paraffin sections
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	The monclonal antibody HM.2 reacts with the 90 kD glycoprotein Intracellular Adhesion Molecule-1 (ICAM-1). The adhesion molecule ICAM-1 belongs to the immunoglobulin superfamily, C2 subset; it is a ligand for the Integrins LFA-1 and MAC-1 and for CD43. ICAM-1 is a essential component in many immune-related processes. ICAM-1 links with receptors of the integrin family, thereby mediating cell-cell interactions and allowing for signal transduction. ICAM-1 interacts specifically with its receptors to induce a reversible adhesion interaction. For processes like T cell activation and leucocyte recruitment, normal immune function relies on ICAM-1. Therefore, it is understandable that alterations in ICAM-1 structure or expression are associated with immune disorders. It is important to properly understand the various functions and regulatory mechanisms of ICAM-1, the resulting disease-related failures, and the various treatments. ICAM-1 is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. Upon cytokine stimulation, the concentrations greatly increase. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFalpha) and is expressed by the vascular endothelium, macrophages and lymphocytes
Immunogen	n/a
Other Names	ICAM-1, CD54
Gene, Accession #	n/a
Catalog #	HM2104BT
Price
Order / More Info	ICAM-1, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產品資料

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