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產(chǎn)品名稱

Recombinant Mouse TACI-Fc Chimera (carrier-free) from BIOLEGEND

產(chǎn)品貨號

577708

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

500 μg

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Mouse TACI-Fc Chimera (carrier-free)
Description	Transmembrane activator and calcium-modulator and cytophilin ligand interactor (TACI) is a TNFR family member molecule and is part of the so-called BAFF system. This includes two ligands: B cell-activating factor of the TNF family (BAFF) and a proliferation-inducing ligand (APRIL), and three receptors: BAFFR (TNFRSF13C), TACI (TNFRSF13B), and B cell maturation Ag (BCMA or TNFRSF17). BAFF binds the three receptors, while APRIL binds TACI and BCMA. TACI is constitutively expressed on na?ve B cells and is upregulated on activated B cells. TACI levels are severely reduced in newborn mice B cells compared with those of adult mice, and newborn B cells do not secret Igs when they are stimulated with BAFF or APRIL. This reduced TACI expression might be responsible for the irresponsiveness of newborn B cells to T cell independent type II antigens such as bacterial capsular polysaccharides.
Size	500 μg
Concentration	n/a
Applications	BA
Other Names	TNFRSF13B
Gene, Accession, CAS #	Gene ID: 57916
Catalog #	577708
Price
Order / More Info	Recombinant Mouse TACI-Fc Chimera (carrier-free) from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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