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產(chǎn)品名稱

ARRY-520 from CAYMAN CHEMICAL COMPANY

產(chǎn)品貨號(hào)

21883-5

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

5 mg

產(chǎn)品品牌

CAYMAN CHEMICAL COMPANY

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Product Name	ARRY-520
Description	A potent Eg5 inhibitor (IC50 = 6 nM); selective for Eg5 over a panel of 8 kinesins (IC50s = >100 μM) and a panel of 224 kinases at 10 μM; induces time-and dose-dependent cell death in HL-60, Jurkat, OCI-AML3, U937, and MOLM-13 leukemic cells; induces cell cycle arrest at the G2/M phase in a p53- and XIAP-independent manner in OCI-AML3 cells; inhibits blast colony formation of bone marrow samples derived from human AML patients; completely eliminates tumors in the RPMI-8226 multiple myeloma and HL-60 and MV4-11 AML mouse xenograft models at 20 mg/kg per day ,
Size	5 mg
Concentration	n/a
Applications	n/a
Other Names	Filanesib
Gene, Accession, CAS #	CAS: 885060-09-3
Catalog #	21883-5
Price
Order / More Info	ARRY-520 from CAYMAN CHEMICAL COMPANY
Product Specific References	n/a
產(chǎn)品資料

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