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產(chǎn)品名稱

Recombinant Human Telomerase reverse transcriptase (TERT), partial from BIOMATIK

產(chǎn)品貨號

RPC22099

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

100ug

產(chǎn)品品牌

BIOMATIK

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	Recombinant Human Telomerase reverse transcriptase (TERT), partial
Description	Purity > 85% as determined by SDS-PAGE. MW: 22.7kDa. Partial: 281-436aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
Size	100ug
Concentration	n/a
Applications	RUO
Other Names	HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2
Gene, Accession, CAS #	TERT, UniProt: O14746
Catalog #	RPC22099
Price
Order / More Info	Recombinant Human Telomerase reverse transcriptase (TERT), partial from BIOMATIK
Product Specific References	n/a
產(chǎn)品資料

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